Medications like Mounjaro and Zepbound contain tirzepatide and are prescribed for metabolic conditions
some clinicians may start at the lower end (0.2 mg) and adjust based on IGF-1 levels and clinical response
The CANVAS (Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes) trial revealed lower risk for death from cardiovascular causes, nonfatal myocardial infarction, and nonfatal stroke in patients with established type 2 diabetes and cardiovascular disease treated with canagliflozin in comparison to placebo
The gap narrows significantly at higher doses
The article says persistent or severe bruising deserves immediate provider contact, and gives concrete signals: swelling larger than two inches, pain, or warmth, which need evaluation to exclude a hematoma or infection
Another hidden factor is the connection between menopause and cardiovascular health