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People with existing conditions that affect immunity should discuss these risks with their healthcare provider

Reducing frequency temporarily or applying a light, non-comedogenic moisturizer can help minimize irritation during the adjustment period

Further research is needed to explore the long-term efficacy and safety of these interventions in clinical settings

10.1016/j.mcn.2012.10.003 43 DoaeiS.BourbourF.TeymooriZ.JafariF.KalantariN.Abbas TorkiS.et al (2021)

Niacinamide (Vitamin B3) Niacinamide, also known as Vitamin B3, is another active ingredient often found in skin-brightening products, and it is included in Dabo 30 Days Glutathione Snow White Melanope Toner for its multiple skin benefits

The evening application is arguably more important than morning because it supports overnight repair processes