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Glutathione regulates melanin production by inhibiting tyrosinase, the enzyme that triggers pigmentation

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Furthermore, using redox-sensitive GFP2 (roGFP2) 9,34,35 as a tool for functional analysis of glutaredoxins, we determined that the inactive monothiol glutaredoxin AtGrxS15 from Arabidopsis thaliana 36 is able to utilize glutathione disulfide (GSSG) but not GSH as a substrate