surmount studies tirzepatide SURPASS to SURMOUNT: The Trials To Know SURMOUNT‐4 study design. This is

How will we monitor for both effectiveness and potential complications

Your meal timing does not affect the medications absorption or efficacy

A meta-analysis of randomized controlled trials found they can improve tendon structure, strength, and post-exercise recovery when combined with resistance training, though the quality of evidence remains moderate. Innovation is exciting, but recommending injectable, unregulated peptides to patients, without clinical validation should give us pause

Retatrutide, an investigational triple GIP, GLP-1, and glucagon receptor agonist, has produced substantial weight loss in phase 2 obesity trials and promising topline phase 3 results

Key Takeaways GLP-1 medications like semaglutide (Wegovy, Ozempic), tirzepatide (Zepbound, Mounjaro), and orforglipron (Foundayo) are available online through telehealth and licensed pharmacies

SPRINZ, H., MATZKE, H., & CARTER, J