pCS also promote the expression of inflammatory factors and adhesion molecules in macrophages and cultured endothelial cells (86, 87)
Additionally, a positive feedback loop involving IL-6 secretion from fibroblasts and arginase-1 induction in macrophages further amplifies the fibrotic cascade [76]
By forming nonreactive molecules, Glutathione neutralizes hydrogen peroxide as well as oxygenated radicals that have disruptive effects on lipids, proteins, enzymes, and cellular DNA.
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