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Molecules 28 , 3500 (2023)

[DOI] [PubMed] [Google Scholar] 28.Klaassen CD, Liu J, Diwan BA

this bacterium produces anti-inflammatory metabolites (e.g., butyrate androsmarinic acid) that downregulate the expression of TLR4 and CD14 (Cluster of Differentiation 14) on intestinal macrophages, limiting LPS (Lipopolysaccharides)-induced inflammatory responses (132, 134)

The study was conducted on 32 male mice divided into four groups: a control (C) group receiving a standard diet with biotin, a biotin-deficient (BD) group on a biotin-free diet, a ketogenic control (KC) group on a ketogenic diet (low-carbohydrate and high-fat) with biotin, and a ketogenic biotin-deficient (KBD) group on a ketogenic diet without biotin

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