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Its tri-agonist receptor activity supports research into receptor pharmacology, endocrine pathway regulation, lipid metabolism, hepatic signaling, and cross-tissue metabolic communication in controlled laboratory and translational research environments [1][5]

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Being overweight or obese is associated with more than 200 diseases, including cardiovascular disease, type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnoea, certain cancers, and metabolic dysfunction-associated steatotic liver disease (MASLD) [9]

New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays

doi: 10.3390/antiox9121236 209 Parra-CotaF