In the head-to-head DREAMS-3 trial, mazdutide 6 mg produced greater weight loss (10.29% vs 6.00%) and better glycemic control than semaglutide 1 mg at 32 weeks
This was often accompanied by enrichment of pro-inflammatory Proteobacteria and depletion of protective phyla such as Verrucomicrobia, indicating a shift toward inflammation and barrier dysfunction (Stolfi et al., 2022)
During your first visits, we typically meet in person to ensure a thorough evaluation
Maintaining consistent hydration and electrolyte balance is a non-negotiable part of safe GLP-1 therapy in this population
The most well-known and biologically active form in humans is alpha-tocopherol
Most gut peptide research has been conducted in rodent models, and while the mechanistic data is compelling, translation to human outcomes has not been established through large clinical trials