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[33] These multiple mechanisms of action may work synergistically to produce the broad anti-inflammatory and immunosuppressive effects observed with prednisone therapy

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3 Background Psoriasis results from a complex interaction of the immune cells, skin cells, and inflammatory messengers called cytokines, resulting in an inflammatory cascade that affects not only the skin but tissues throughout the body (Monteleone 2011

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This clear distinction is indicated on the labels of research chemicals, exempting them from specific regulations under Title 21, Parts 100-740 of the Code of Federal Regulations (21CFR)