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PMID: 27856930

113 Thus, through the coordinated activation of GSH production, utilization, and regeneration, Nrf2 ensures maintenance of the intracellular levels of reduced GSH

Additionally, because NAC possesses mild blood-thinning properties by breaking disulfide bonds in clotting factors, taking it alongside anticoagulants or antiplatelet drugs can increase the risk of bruising and bleeding

Risk factors for ASCVD include hypertension, hyperglycemia, hyperlipidemia, smoking, and obesity (Wang et al., 2018)

10.1038/nchembio.2414 46 SchneiderC