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Crevasse is characterized by a cluster of hydrophobic phenylalanine residues, including Phe279 6.51 , Phe286 6.58 , Phe290 6.62 , Phe309 7.39 , and Phe312 7.42 (Figure 3)

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NF-kappa B is activated during acute inflammation in vivo in association with elevated endothelial cell adhesion molecule gene expression and leukocyte recruitment

The remaining author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest