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An in vitro study performed by Magalhes-Padilha et al., demonstrated a higher growth rate of IGF-1 stimulated caprine preantral follicles and they stipulated that it was most likely due to cellular proliferation, as it was demonstrated that IGF-1 enhanced nuclear maturation of granulosa cells in preantral follicles (63)

Route: Subcutaneous injection (abdomen, thighs, or upper arms)

10.3389/fnmol.2022.965697 21 ChenH.KanQ.ZhaoL.YeG.HeX.TangH.et al (2023)