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In general, long- and prolonged-acting GLP-1 analogs increase heart rates while short-acting GLP-1 analogs do not [30]

When older individuals have been studied, analyses from trials such as Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation (ADVANCE) suggested that more frail individuals have worse outcomes and benefit less from intensive control of blood glucose levels and blood pressure [263]

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10.1016/j.cub.2014.12.049 7 BoraldiF.BartolomeoA.Di BariC.CocconiA.QuaglinoD

The reconstructive strategy for improving elbow flexion in late obstetric brachial plexus palsy