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doi: 10.1124/jpet.103.051987 89 DeYoungMBMacConellLSarinVTrautmannMHerbertP

When GLP-1 receptors are activated, they promote insulin secretion, reduce glucagon production, slow down gastric emptying, and increase satiety

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Methods and Procedures: Glucose turnover during two, 2-h, euglycemic clamps was measured in 12 lean and 12 obese (BMI 30 kg/m2) male and female subject volunteers with normal oral glucose tolerance test

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If a severely obese patient (BMI 35 to 39.9) with one or more health conditions, or a morbidly obese patient (BMI 40 or greater), has not reached 10% TBWL in six months, they should be referred for bariatric surgery