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The positive correlations in human CSF of Xan and several monoamines including 5-HIAA have been noted earlier ( PURINERGIC SIGNALING, CLINICAL IMPROVEMENT, AND NEUROLOGICAL DEFICITS Associations between purine metabolites and clinical and neurological symptoms were examined before and after 4w antipsychotic treatment ( greater improvement in clinical functioning 1 month later ( Figure 4 )
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"Design, Synthesis and Biological Evaluation of Neogliptin, a Novel 2-Azabicyclo[2.2.1]heptane-Based Inhibitor of Dipeptidyl Peptidase-4 (DPP-4)"
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