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The key is progressive loading: gradually increasing the challenge over time so the muscles continue to receive a growth and maintenance stimulus

This occurs because Ozempic increases insulin sensitivity while decreasing glucose absorption into the circulation

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Lancet 2021;398:216072.ArticlePubMed 100

Open-field test Locomotor activity was evaluated using an open-field test

Both medications improve glucose control, but tirzepatides dual mechanism may offer additional benefits for patients with insulin resistance or prediabetes Budget considerations