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As of October 2024, a handful of these products are in late-phase clinical trials, with active ingredients such as retatrutide, survodutide and ecnoglutide, and more than 18 other drug candidates are in earlier stages of development

The strongest improvements show up in triglycerides and total cholesterol-to-HDL ratios rather than broad LDL reduction

Staying well-hydrated, ensuring proper sleep, and managing stress can help alleviate headaches

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They may also be able to recommend medications or other ways to help manage those side effects