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In summary, in addition to a centrally-mediated COX inhibition mode of action, vanilloid and cannabinoid signaling pathways are also implicated in pharmacological actions of APAP (34)
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From the first evidence regarding the involvement of GSH in apoptosis, up to date many improvements have been made, and growing results, which attempted to dissect the mechanisms linking GSH to cellular redox-dependent processes, were added
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