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In fact, mice with reduced levels of NAMPT, such as genetic NAMPT heterozygous mice, showed low glucose tolerance due to impaired insulin secretion

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Indeed, the high heterogeneity observed in the present study also corroborates the wide variation of GSH concentrations across different studies and laboratories

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Moreover, under hypoxic conditions, the activation of autophagy and mitophagy can reduce ROS production and protect cells from oxidative damage [255]