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246 Sepsis often triggers a sepsis-associated encephalopathy (SAE) which presents itself with wide symptomatology including reduced attention, disrupted sleep-wakefulness balance, impaired speech and orientation, deficient leaning and memory, numerous perception disorders, focal neurological deficits, seizures, and, in terminal stages, coma

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Fourth, the duration of the trial, 32 weeks, was insufficiently long to demonstrate the durability of glycemic and weight effects of CagriSema [10]

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Morphological changes of reactive astrocytes have long been recognised not only after traumatic injuries but also in many other pathological contexts

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