Di Cairano ES, Davalli AM, Perego L, et al
Interestingly, when compared to the GN-treated group, the carrier NPs-CS and -spanlastics did not significantly modify renal parameters, indicating that they did not worsen damage processes or impair baseline renal function
In the NEJM Phase 2 trial, participants assigned to an initial dose of 4 mg experienced significantly more adverse events than those who started at 2 mg, even when both groups ultimately reached the same target dose
In support of its pro-longevity profile, researchers have noted that higher MOTS-c levels correlate with healthier aging markers in both animals and humans, implying that maintaining MOTS-c might benefit aging tissues
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