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By increasing Ca 2+ influx and consequently insulin granule exocytosis, both pathways work together to promote insulin secretion

A single-chain antibody-CD39 fusion protein targeting activated platelets protects from cardiac ischaemia/reperfusion injury

We are grateful to the patient with the R152H variant and the patients parent for providing their fibroblasts for this study

It appears to normalize NO levels, which can be dysregulated during injury or inflammation