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Most patients experience peak discomfort during dose escalation phases, particularly when jumping to a new weekly injection strength

Although lifestyle interventions (low-calorie diets and exercise) are still the cornerstone of weight management, weight loss achieved through this approach is extremely difficult to sustain in the long term, particularly due to physiological adaptations that reduce the energy expended or increase appetite to compensate for the missing calories

Wahlqvist ML, Lee M-S, Hsu C-C, Chuang S-Y, Lee J-T, Tsai H-N

La evidencia de investigacin fisiolgica y nutricional sugiere que ciertos patrones de alimentacin se asocian a una mayor produccin natural de GLP-1: comidas con buena cantidad de fibra fermentable (verduras, leguminosas, avena, inulina), suficiente protena y menos ultraprocesados

Discuss all medications with your clinician