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In the geography of the cell this series has been drawing, alpha-lipoic acid is the molecule that crosses between neighbourhoods a sulphur-bearing compound that belongs, in a sense, to the whole map rather than to one district of it

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The availability of glutamine is crucial in SCD because the NADH:[NAD + + NADH] (redox) ratio in sickle red blood cells (RBCs) is less than it is in healthy RBCs, indicating oxidative stress