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Both of which regulate mitochondrial biogenesis and shift substrate utilization from glucose toward fatty acid oxidation

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Its research profile makes it especially relevant for studies focused on fat-cell pathway models, metabolic turnover, energy-balance signaling, methylation-adjacent biology, and body-composition pathway research

Two phase 3 trials BLOOM (Behavioral modification and Lorcaserin for Overweight and Obesity Management) and BLOSSOM (Behavioral modification and LOrcaserin Second Study for Obesity Management) evaluated obese and overweight patients to demonstrate the efficacy of lorcaserin (10 mg twice daily) over placebo [83.84]

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