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[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Severino P., DAmato A., Netti L., Pucci M., Infusino F., Maestrini V., Mancone M., Fedele F

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Weight loss plateaus are common on a GLP-1 medication and usually reflect your body adapting not the medication stopping

A First Look at the Numbers A 2026 study published in The Lancet Obstetrics, Gynaecology, and Women's Health took a direct look at this question, evaluating 120 postmenopausal women treated with tirzepatide, one of the most effective GLP-1 and GIP dual receptor agonists currently available [16]

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