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Neuron 21 : 521530

With regard to the patient, autoimmune markers, including islet cell autoantibodies, autoantibodies to GAD (GAD65) and insulin were negative, basal C-peptide was 4.19 ng/ml (reference range 0.81-4.5 ng/ml) and there were no signs of acanthosis nigricans

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In research settings, Melanotan II is of interest due to its interaction with melanocortin receptors, particularly pathways associated with melanin production, pigmentation biology, cellular response to UV exposure, and broader melanocortin system activity

GLUT4 pathway and glucoseWWP1 interaction Impaired glucose uptake is a key feature of insulin resistance in sarcopenia and T2D [85] (Fig