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(PubMed) Farebrother J, Zimmermann MB, Andersson M
Dipeptidyl-peptidase-4 (DPP-4) inhibitors (or gliptins) represent a class of oral anti-hyperglycemic agents that block the inactivation of the incretin hormones, namely glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), and thus affect glucose control through several mechanisms, including enhancement of glucose-dependent insulin secretion, slowed gastric emptying, and reduction of postprandial glucagon and of food intake (Scheme 1) [9]
doi: 10.3389/fnut.2025.1746176 Received 14 November 2025 Revised 03 December 2025 Accepted 17 December 2025 Published 12 January 2026 Volume 12 - 2025 Edited by Iris Joye, University of Guelph, Canada Reviewed by Soubhagya Tripathy, Indian Institute of Technology Kharagpur, India Prakasha R., Anand Agricultural University, India Updates Copyright 2026 Hao, Tan, Liu and Xin
Histidine Histidine is one of the essential amino acids, histidine decarboxylase (HDC) catalyses the production of histamine from histidine and is highly expressed in DCs
"Some people weigh significantly less than when they started GLP-1s, which would contribute to a lower alcohol tolerance," Chao noted
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