Best taken on an empty stomach at least 10 minutes before a meal
every 23 days) is practical, whereas local patients might opt for weekly injections depending on physician preference
Konopleva M, Hayes K, Pierce S, Zhao L, Andreeff M , Glasman E, Freireich E, Estey E
Exclusion criteria: (1) Patients with abnormal coagulation function [limits: prothrombin time (PT) between 1014 seconds, activated partial thromboplastin time (APTT) between 2540 seconds, and fibrinogen (Fib) levels between 2.04.0 g/L] and immunodeficiency [either primary immunodeficiency (congenital or hereditary conditions leading to impaired immune responses) or secondary immunodeficiency (conditions acquired through HIV infection, chronic immunosuppressive therapy, or severe malnutrition)]
Ultimately, the diaphragm rapidly moves cranially, resulting in positive intrathoracic pressure that leads to expulsion of these contents
A single 30mg vial can cover weeks 1 through 6 of a standard titration (10mg + 20mg = 30mg), while the same coverage requires 3 separate 10mg vials
