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It is a clinical observation and occurs in a variety of other conditions, including DM, polymorphous light eruption, photoallergic contact dermatitis, solar urticaria, and porphyrias

This balanced approach to inflammation is critical for efficient tissue repair, as some inflammatory processes are necessary for clearing debris and initiating regeneration

Furthermore, if SubP does mediate cigarette-induced secretion of goblet cells, then it is possible that it might also contribute to increased expulsion of mucus in COPD airways and/or regulate muc5AC and muc5B expression