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Type 1 diabetes, diagnosed in 510% of diabetes, is an autoimmune alteration of -cells in the pancreas by CD4 + and CD8 + T cells

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In both trials, male and female subjects aged 1875 years with a body mass index of 20.029.9 kg/m 2 were eligible to participate if they were in good general health

USA 112 , 61346139 (2015)

SERIOUS INFECTIONS (5.1, 6.1): Increased risk of serious infections leading to hospitalization or death, including tuberculosis (TB), bacterial sepsis, invasive fungal infections (such as histoplasmosis), and infections due to other opportunistic pathogens

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