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Both groups show reduced abundance of intestinal bacteria Roseburia , including Ruminococcus gnavus and Ruminococcus , while the abundance of Blautia increases

All assays were performed in cells maintained at ~60% confluency

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[1] [2] For patients with documented hypersensitivity to other GLP-1 receptor agonists (such as semaglutide, dulaglutide, or liraglutide), cross-reactivity is uncertain due to differences in molecular structure

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The GLP-1 receptor activation happens throughout the central nervous system, including areas involved in pain perception and blood vessel regulation