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PHILADELPHIA Periodontal diseases, commonly known as gingivitis and periodontitis, remain a significant global health challenge, affecting nearly 60% of adults aged 65 and older and contributing to substantial medical, psychological, and financial burdens

Gallotti, F., Lavoisier, A., Turchiuli, C., & Lavelli, V

Clinical constipation is defined as fewer than 3 bowel movements per week, often accompanied by hard stools requiring excessive straining and incomplete evacuation feeling

Badiudeen et al., 2019)

A 2016 study in Cellular and Molecular Gastroenterology and Hepatology showed that KPV dramatically reduced colonic tumorigenesis in a model of colitis-associated cancer an effect that was abolished in PepT1-knockout animals

TB500 is a synthetic heptapeptide (7 amino acids) derived from the actin-binding region of thymosin beta-4