Maintains healthy lipid metabolism and oxidative status
The Insulin Paradox: How GLP-1 Drugs Reduce Belly Fat and Heart Risk Dr Edward Leatham Dec 13, 2025 7 min read Updated: Apr 21 An article by Dr Edward Leatham, Consultant Cardiologist For busy people, or to tune in when on the move, Google Notebook AI audio podcast are available for this story beneath
For oral use, doses of up to 500 mg daily for two months are typically well-tolerated
Tirzepatide's dual mechanism may increase gastrointestinal side effects in some patients, while semaglutide has longer real-world safety data
Additionally, clinical trials with larger sample sizes and longer follow-up periods are needed to further validate the efficacy of these strategies and to identify potential side effects and contraindications
The Journal of Allergy and Clinical Immunology: In Practice , 3 (5), 702-708