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No pharmacokinetic interaction has been established between semaglutide and common SSRIs, but the shared appetite-suppressive effects of some antidepressants (notably bupropion) and GLP-1 agonists can produce additive nausea in the first four to eight weeks of concurrent use

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Weight loss Wegovy (semaglutide) tablets and injections are prescription medications used for weight loss, long-term weight management, and to reduce the risk of major cardiovascular events in certain patients with obesity or who are overweight