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Effects on mental health and cognition Over time, chronic substance misuse can lead to severe mental health issues

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Interestingly, Liraglutide 10100nM increased adiponectin ( ADIPOQ) expression [13] and in one study it led to an initial upregulation of PPAR and C/EBP followed by a significant downregulation, while preadipocyte marker Pref-1 was gradually increased [20]

10.1111/j.1365-2133.2006.07165.x [DOI] [PubMed] [Google Scholar] 72.Esteva A et al

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R.DudekH.TaoX.MastersS.FuH.GotohY.et al (1997)