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Description

Smith, A

Both peptides are short-acting, and observed timing depends on study design and experimental conditions

For MIG-6L::mNG quantifications (Supplementary Fig

However, there are only a few systematic studies on this mechanism, and the specific mechanism is still unclear

Sterling et al., 2020

Through complex signaling networks involving IGF receptors and regulatory proteins, IGFs promote smooth muscle cell proliferation, extracellular matrix accumulation, and endothelial cell dysfunctionaggravating vascular alterations characteristic of the disease