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Women who are pregnant or breastfeeding, those planning for pregnancy, or individuals who have kidney or liver problems should consult an experienced physician before beginning treatment with semaglutide

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The most striking recent piece of evidence came from a 2026 study published in Cell Metabolism [12], which found that semaglutide appeared to reverse cartilage damage in a mouse model of osteoarthritis, and crucially, this effect was independent of weight loss