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Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel

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In summary, the results presented here establish DA as a modulator of glucagon and insulin secretion via its actions on both adrenergic and dopaminergic receptors in human and mouse islets

Azevedo EP, Guimaraes-Costa AB, Bandeira-Melo C, Chimelli L, Waddington-Cruz M, Saraiva EM, Palhano FL, Foguel D