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But I'm not sure whether it will affect mobilization of liver stores of B12

You may notice that different sources quote different shelf-life figures (12 months, 24 months, even 36 months)

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For some chemicals, they may instead lead to an increase in toxicity (toxication)

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Kwaaitaal M, Huisman R, Maintz J, Reinstdler A, Panstruga R (2011) Ionotropic glutamate receptor (iGluR)-like channels mediate MAMP-induced calcium influx in Arabidopsis thaliana