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, Metabolic Concepts in Idiopathic Intracranial Hypertension and Their Potential for Therapeutic Intervention
Metabolism of fats, carbohydrates and proteins
They feed the gut bacteria that produce short-chain fatty acids, which in turn stimulate GLP-1 secretion
These are a newer class of DMARDs that target specific parts of the immune system
Collectively, this feed-forward TGF-ROS circuit sustains myofibroblast differentiation and fibrotic matrix deposition
In vitro, C16-carnitine has been found to activate specific subsets of neurons in the dorsal root ganglia (DRGs) of muscles that play a key role in sensing muscle fatigue or exertion and are involved in transmitting these sensory signals to the CNS, indicating that C16-carnitine acts as a signaling molecule for muscle afferent nerves [281]
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