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Patients presenting with post-inflammatory hyperpigmentation from acne or sun damage, which is especially prevalent in South Floridas Fitzpatrick III through VI population, see meaningful tone evenness improvements alongside texture changes

Over time, exposure to environmental pollutants, processed foods, alcohol, and medications can overwhelm the liver, leading to poor detoxification and increased oxidative stress[7]

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Additional oral supplementation with polypodium leucotomos extract (PLE) at 480 mg twice daily can be helpful (anecdotal evidence, unpublished)

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