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Patients on semaglutide who have low or borderline B12 levels may notice reduced fatigue when B12 is added to their treatment plan, since the vitamin supports the metabolic processes that keep energy levels steady during weight loss

China doubled its peptide exports to the US in 2025, with shipments approaching half a billion dollars, much of it reaching consumers through platforms like Temu with no guidance on purity or what the product actually contains

This makes semaglutide not only the most clinically effective but also the most commercially successful weight loss medication in history