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The latter is still the gold standard technique for assessing the epithelial barrier function, whereas in vivo techniques, including putative blood biomarkers such as intestinal fatty acid-binding protein and zonulin, are broadly used despite limitations
In 2021, plasma samples from the validation cohort were collected from 102 sibling pairs (102 unaffected and 102 konzo affected, 98 sex-matched, 4 pairs who are discordant for sex) in the Kahemba region of the Democratic Republic of the Congo
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However, several species involved in LC metabolism also produce short-chain fatty acids (SCFAs), which are necessary for intestinal health
By revealing subtype-specific molecular and biological pathways, we aim to identify candidate biomarkers and elucidate the distinct molecular mechanisms that may contribute to the heterogeneous clinical trajectories of PD
L- 1500
