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Effects on Weight Loss and Glycemic Control of Retatrutide, a Glucose-Dependent Insulinotropic Polypeptide, Glucagon-Like Peptide-1, and Glucagon Receptor Triagonist, in a Surrogate Model for Nonalcoholic Steatohepatitis in Mice

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It slows gastric emptying, increases feelings of fullness, and leads to decreased appetite

Patients need to stay on these drugs, Moore said

Most of the plausible benefit is likely weight- and hepatic-fat-mediated, which would help the many women with PCOS whose insulin resistance is weight-driven

The most common side effects are gastrointestinal and tend to be temporary, particularly during dose increases