(2019) Erastin, a ferroptosis-inducing agent, sensitized cancer cells to X-ray irradiation via glutathione starvation in vitro and in vivo , PLoS One , 14 , 0225931, doi: Louandre, C., Marcq, I., Bouhlal, H., Lachaier, E., Godin, C., Saidak, Z., Francois, C., Chatelain, D., Debuysscher, V., Barbare, J.-C., Chauffert, B., and Galmiche, A
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Capsaicin, derived from chilli peppers, is thought to increase thermogenesisthe production of heat in the bodythereby burning additional calories
For example, the Phase 2 ELAD trial of liraglutide in Alzheimer's disease did not meet its primary cognitive endpoints, though some secondary measures showed potential signals
In drug development, high lipophilicity is frequently preferred, especially for intracellular medicines
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