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Throughout the follow-up period, HbA1C levels remained consistently higher in the GLP-1 RAs group (Figure S1)
The ability of peripherally circulating GLP-1 and GLP-1RAs to breach the blood-brain barrier remains uncertain
Despite shorter duration, oral semaglutide can still produce meaningful weight loss when taken consistently each day, as sustained daily intake maintains therapeutic blood levels
The logic behind three times weekly dosing relates to semaglutide half-life
What Is a GLP-1
Lotte Bjerre Knudsen (30:46): We are in the process of trying to see if we could take those signatures and apply them on to our data
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