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Dr Amit Langote, nephrologist, kidney transplant physician and hypertension specialist at Apollo Hospitals, Navi Mumbai, had handled one such case in 2023, where glutathione shots had badly damaged the kidneys of a 28-year-old woman with no prior comorbidities

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The TMAO precursor and rate-limiting synthesis factor, trimethylamine (TMA), is produced by the gut microbiome from dietary choline, phosphatidylcholine, betaine and L-carnitine [18, 19]

Reduced GAPDHS activity leads to decreased pyruvate carboxylase function and impaired aspartate synthesis, ultimately altering the metabolic profile of metastatic melanoma