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(2018) found that GHK modulated the expression of over 4,000 human genes

Another member of the natriuretic peptide family, A-type natriuretic peptide (ANP), which also has diuresis activity, was shown to be stimulated by exenatide, a GLP-1 receptor agonist (72, 108)

Individual responses vary, which is why baseline colitis assessment and close monitoring during the first 48 weeks of treatment are essential

These include pancreatitis (rare but reported in clinical trials and post-marketing surveillance), gallbladder disease, and acute kidney injury (particularly in the setting of severe dehydration from gastrointestinal effects)

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