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Consequently, zinc deficiency is common in vegans who exclude animal products, as well as in patients with nephropathies, malabsorptive gastrointestinal diseases, cancer and diabetes

Mounjaro and Zepbound warn about this explicitly on their labels, but Ozempic and Wegovy only warn more broadly about absorption of any drugs taken by mouth

Busam KJ, Iversen K, Coplan KC, et al

For marketers, this tension is crucial

Fluid overload is another risk, especially for people with heart or kidney issues

The recommended washout period differs by product: the UK Summary of Product Characteristics (SmPC) for semaglutide (Wegovy) advises stopping treatment at least two months before a planned pregnancy, whilst the SmPC for tirzepatide (Mounjaro) advises stopping at least one month before